Little Horn

BossAfterbirthUnlock unknown

Encounter details

Game ID: 404
Environment: Boss / Basement / Cellar / Burning Basement / boss challenge / Boss Rush / Double Trouble / Depths / Necropolis / (with Rag Man) / Dank Depths / (with Loki) / Womb / Utero / (with The Fallen) / Scarred Womb / (with Big Horn) / Degraded Boss / Sheol / Chest / Dark Room
Description: Little Horn is a boss added in The Binding of Isaac: Afterbirth that can appear in all environments of Chapter 1 (Basement, Cellar, Burning Basement).

How do you unlock Little Horn?

Needs researchNo validated unlock requirement has been imported yet.

Little Horn is a boss added in The Binding of Isaac: Afterbirth that can appear in all environments of Chapter 1 (Basement, Cellar, Burning Basement).

This path has not yet been revealed

This requirement hasn't been imported yet.

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What unlocking Little Horn leads to

Nothing depends on this yet.

Source: bindingofisaacrebirth.wiki.gg

Imported 2026-09-13