Mother

BossRepentanceUnlock unknown

Encounter details

Game ID: 912
Environment: Boss / Corpse
Description: Mother is a boss added in The Binding of Isaac: Repentance and the only boss of the second floor of the Corpse, as well as the final boss of Ending 21.

How do you unlock Mother?

Needs researchNo validated unlock requirement has been imported yet.

Mother is a boss added in The Binding of Isaac: Repentance and the only boss of the second floor of the Corpse, as well as the final boss of Ending 21.

This path has not yet been revealed

This requirement hasn't been imported yet.

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What unlocking Mother leads to

Jacob and Esau
Isaac's Awakening
Seeing Double
A Strange Door

Source: bindingofisaacrebirth.wiki.gg

Imported 2026-09-13