
2 of Hearts
CardRebirthUnlocked
How do you unlock 2 of Hearts?
Verified starting unlockSource data confirms that no unlock is required.
Doubles Isaac's current number of Red Hearts. If Isaac only has empty Red Heart containers, he is healed for 1 Red Heart.
Available from the start
No unlock needed — this is available in every new save file.
What unlocking 2 of Hearts leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13