Ace of Hearts
CardAfterbirth+Locked
How do you unlock Ace of Hearts?
In The Binding of Isaac, Ace of Hearts is unlocked by unlocking Living on the edge.
Structured pathSource-backed requirements are mapped into trackable steps.
Turns all pickups, trinkets and chests in the room into hearts. All non-boss enemies in the room are also transformed into hearts.
How to unlock: Complete a Chapter (floors I and II) after Basement, start-to-finish, with only half a Heart total (can use The Lost)
What unlocking Ace of Hearts leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13