
Betrayal
ItemAfterbirthLocked
passiveGame ID 391★★★★
How do you unlock Betrayal?
In The Binding of Isaac, Betrayal is unlocked by earning the Hush completion mark as Judas (Character).
Structured pathSource-backed requirements are mapped into trackable steps.
[Before Repentance] Charms all enemies in the room when Isaac takes damage. / [Repentance] Enemies are able to damage each other. If an enemy is damaged by another enemy, they will attack that enemy instead of Isaac.
See the full unlock path for Betrayal — 5 stepsWhat unlocking Betrayal leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13