Bob's Brain
ItemRebirthUnlocked
familiarGame ID 273★★★★
How do you unlock Bob's Brain?
Verified starting unlockSource data confirms that no unlock is required.
Spawns a familiar that charges forward when shooting tears and explodes upon contact with an enemy, damaging and poisoning them. The familiar respawns after a few seconds.
Available from the start
No unlock needed — this is available in every new save file.
What unlocking Bob's Brain leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13