Book of Virtues
ItemRepentanceLocked
activeGame ID 584★★★★
How do you unlock Book of Virtues?
In The Binding of Isaac, Book of Virtues is unlocked by earning the Isaac completion mark as Bethany (Character).
Structured pathSource-backed requirements are mapped into trackable steps.
Passively causes active items to spawn themed orbital wisp familiars on use, which fire tears and block shots. Can be activated to spawn a basic wisp if Isaac has no other active item.
What unlocking Book of Virtues leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13