Box of Friends
ItemAfterbirthLocked
activeGame ID 357★★★★
How do you unlock Box of Friends?
In The Binding of Isaac, Box of Friends is unlocked by earning the Ultra Greed completion mark as Lilith (Character).
Structured pathSource-backed requirements are mapped into trackable steps.
Duplicates all of Isaac's familiars for the current room. If Isaac has no familiars, spawns a Demon Baby for the room instead.
See the full unlock path for Box of Friends — 7 stepsWhat unlocking Box of Friends leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13