
Buddy in a Box
ItemAfterbirth+Locked
familiarGame ID 518★★★★
How do you unlock Buddy in a Box?
In The Binding of Isaac, Buddy in a Box is unlocked by unlocking Buddy in a Box (Achievement).
Structured pathSource-backed requirements are mapped into trackable steps.
Spawns a familiar with a random tear effect. The familiar is randomized at the start of each floor.
How to unlock: Pick up 5 familiars in a single run
What unlocking Buddy in a Box leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13