Clear Rune
ItemRepentanceLocked
activeGame ID 263★★★★
How do you unlock Clear Rune?
In The Binding of Isaac, Clear Rune is unlocked by unlocking Blank Rune (Achievement).
Structured pathSource-backed requirements are mapped into trackable steps.
Copies the effect of the rune or soul stone currently held by Isaac. The recharge time is based on the power of the rune. Drops a random rune when first picked up.
How to unlock: [before Afterbirth+] Complete Onan's Streak (challenge #29) / [Afterbirth+] Complete The Guardian (challenge #30)
What unlocking Clear Rune leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13