D4
ItemRebirthLocked
activeGame ID 284★★★★
How do you unlock D4?
In The Binding of Isaac, D4 is unlocked by unlocking The D4.
Structured pathSource-backed requirements are mapped into trackable steps.
Rerolls all of Isaac's passive items.
How to unlock: Blow up 30 Slot Machine
What unlocking D4 leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13