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Eternal D6

ItemRepentanceLocked

activeGame ID 609★★★★

How do you unlock Eternal D6?

In The Binding of Isaac, Eternal D6 is unlocked by earning the Mother completion mark as ??? (Character).

Structured pathSource-backed requirements are mapped into trackable steps.

Re-rolls all items in the room. Each item has a 25% chance to disappear instead.

See the full unlock path for Eternal D6 — 5 steps

Eternal D6 (Achievement)
- ??? (Character) → Mother (normal)
  1. Defeat Hush 3 times to unlock A Secret Exit. source
  2. After A Secret Exit is unlocked, a locked door to Downpour appears after completing Basement/Cellar/Burning Basement I or II. source
  3. Collect Knife Piece 1 in Downpour/Dross II. source
  4. Collect Knife Piece 2 in Mines/Ashpit II. source
  5. After defeating Mom in Mausoleum/Gehenna II, stab the flesh door that appears with the knife familiar to open it. source
  6. Defeat the Mausoleum version of Mom's Heart behind the flesh door, then reach Corpse II and defeat Mother. source
  - ??? (Character)

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What unlocking Eternal D6 leads to

Nothing depends on this yet.

Source: bindingofisaacrebirth.wiki.gg

Imported 2026-09-13