Euthanasia

ItemAfterbirth+Locked

passiveGame ID 496★★★★

How do you unlock Euthanasia?

In The Binding of Isaac, Euthanasia is unlocked by earning the Delirium completion mark as Lilith (Character).

Structured pathSource-backed requirements are mapped into trackable steps.

Adds a luck-based chance to fire needles that instantly kill basic enemies and deal triple damage to bosses. If a needle kills an enemy, it bursts into more tears/needles.

See the full unlock path for Euthanasia — 7 steps

Euthanasia (Achievement)
- Lilith (Character) → Delirium (normal)
  1. Defeat Hush to unlock The Void. source
  2. A Void portal can appear after a major boss; defeating Hush guarantees one. source
  3. Defeat Delirium, the main boss of The Void. source
  - Lilith (Character)

Show full path Show missing

What unlocking Euthanasia leads to

Nothing depends on this yet.

Source: bindingofisaacrebirth.wiki.gg

Imported 2026-09-13