Experimental Treatment
ItemRebirthLocked
passiveGame ID 240★★★★
How do you unlock Experimental Treatment?
In The Binding of Isaac, Experimental Treatment is unlocked by reaching 7 defeat mom's heart or it lives!.
Structured pathSource-backed requirements are mapped into trackable steps.
[Before Afterbirth+] Randomly increases and decreases some of Isaac's stats. / [Afterbirth+] Increases four random stats and decreases the other two.
- Defeat Mom's Heart or It Lives! (0/7)
What unlocking Experimental Treatment leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13