Giant Cell
ItemRepentanceUnlocked
passiveGame ID 658★★★★
How do you unlock Giant Cell?
Verified starting unlockSource data confirms that no unlock is required.
Causes Isaac to spawn Minisaac familiars when he takes damage, which chase and shoot at nearby enemies.
Available from the start
No unlock needed — this is available in every new save file.
What unlocking Giant Cell leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13