
Guppy's Paw
ItemRebirthUnlocked
activeGame ID 133★★★★
How do you unlock Guppy's Paw?
Verified starting unlockSource data confirms that no unlock is required.
Converts one Red Heart Container into three Soul Hearts.
Available from the start
No unlock needed — this is available in every new save file.
What unlocking Guppy's Paw leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13