
Heartbreak
ItemRepentanceLocked
passiveGame ID 694★★★★
How do you unlock Heartbreak?
In The Binding of Isaac, Heartbreak is unlocked by earning the The Beast completion mark as Tainted Eve.
Structured pathSource-backed requirements are mapped into trackable steps.
Grants 3 broken hearts and +0.25 damage for every broken heart Isaac has. Every otherwise fatal hit will add 2 more until Isaac has nothing but broken hearts.
What unlocking Heartbreak leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13