Holy Water
ItemRebirthUnlocked
familiarGame ID 178★★★★
How do you unlock Holy Water?
Verified starting unlockSource data confirms that no unlock is required.
[Before Repentance] Spawns a bottle familiar that breaks when Isaac takes damage, leaving a puddle of blue creep. / [Repentance] A bottle familiar that flies forward when Isaac shoots. It breaks upon hitting an enemy, leaving a puddle of blue creep that petrifies enemies.
Available from the start
No unlock needed — this is available in every new save file.
What unlocking Holy Water leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13