Infamy
ItemRebirthUnlocked
passiveGame ID 242★★★★
How do you unlock Infamy?
Verified starting unlockSource data confirms that no unlock is required.
Gives Isaac a 50% chance to block projectiles coming from any direction.
Available from the start
No unlock needed — this is available in every new save file.
What unlocking Infamy leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13