Ipecac
ItemRebirthLocked
passiveGame ID 149★★★★
How do you unlock Ipecac?
In The Binding of Isaac, Ipecac is unlocked by reaching 6 defeat mom's heart or it lives!.
Structured pathSource-backed requirements are mapped into trackable steps.
Replaces tears with explosive and poisoning projectiles fired in an arc from the mouth.
- Defeat Mom's Heart or It Lives! (0/6)
What unlocking Ipecac leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13