
Lil Spewer
ItemAfterbirth+Locked
familiarGame ID 537★★★★
How do you unlock Lil Spewer?
In The Binding of Isaac, Lil Spewer is unlocked by unlocking Lil Spewer (Achievement).
Structured pathSource-backed requirements are mapped into trackable steps.
Drops a random pill, and spawns a familiar that charges up and fires creep. Using pills changes the creep type.
How to unlock: Have Isaac die to his own explosion from any explosive and poisoned tear (Ipecac, Bob's Rotten Head, Fire Mind / Explosivo + Scorpio, or a Horf! pill)
What unlocking Lil Spewer leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13