
Little Baggy
ItemRebirthLocked
passiveGame ID 252★★★★
How do you unlock Little Baggy?
In The Binding of Isaac, Little Baggy is unlocked by unlocking Little Baggy (Achievement).
Structured pathSource-backed requirements are mapped into trackable steps.
Isaac can hold 2 pills at once and all cards and runes are replaced by pills.
How to unlock: Pick up 2 syringe-related items in a single run
What unlocking Little Baggy leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13