
Lusty Blood
ItemAfterbirthLocked
passiveGame ID 411★★★★
How do you unlock Lusty Blood?
In The Binding of Isaac, Lusty Blood is unlocked by earning the Ultra Greed completion mark as Samson (Character).
Structured pathSource-backed requirements are mapped into trackable steps.
Isaac's damage increases for the current room each time he kills an enemy.
What unlocking Lusty Blood leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13