Missing No.
ItemRebirthLocked
passiveGame ID 258★★★★
How do you unlock Missing No.?
In The Binding of Isaac, Missing No. is unlocked by earning the Boss Rush completion mark as Lazarus (Character).
Structured pathSource-backed requirements are mapped into trackable steps.
Randomizes all passive items and stats upon pickup and at the start of each succeeding floor.
What unlocking Missing No. leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13