
Mom's Knife
ItemRebirthLocked
passiveGame ID 114★★★★
How do you unlock Mom's Knife?
In The Binding of Isaac, Mom's Knife is unlocked by earning the Satan completion mark as Isaac (Character).
Structured pathSource-backed requirements are mapped into trackable steps.
Isaac's tears are replaced by a knife that pierces enemies, can travel through obstacles, and can hurt enemies while Isaac is holding it. Holding down the fire button before firing increases its range and power.
What unlocking Mom's Knife leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13