Mutant Spider
ItemRebirthUnlocked
passiveGame ID 153★★★★
How do you unlock Mutant Spider?
Verified starting unlockSource data confirms that no unlock is required.
Isaac shoots four tears at once with lower fire rate.
Available from the start
No unlock needed — this is available in every new save file.
What unlocking Mutant Spider leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13