
Mystery Egg
ItemAfterbirth+Locked
familiarGame ID 539★★★★
How do you unlock Mystery Egg?
In The Binding of Isaac, Mystery Egg is unlocked by unlocking Mystery Egg (Achievement).
Structured pathSource-backed requirements are mapped into trackable steps.
Spawns an egg familiar, which hatches a random friendly monster when Isaac is hurt once per room. The power of the monster improves for each consecutive room cleared without taking damage.
How to unlock: Spawn three charmed enemies in the same room
What unlocking Mystery Egg leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13