Polyphemus
ItemRebirthUnlocked
passiveGame ID 169★★★★
How do you unlock Polyphemus?
Verified starting unlockSource data confirms that no unlock is required.
Isaac fires huge tears that deal massive damage, but fire rate is greatly decreased. If a tear kills an enemy, it travels on with any leftover damage.
Available from the start
No unlock needed — this is available in every new save file.
What unlocking Polyphemus leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13