Prayer Card
ItemRebirthUnlocked
activeGame ID 146★★★★
How do you unlock Prayer Card?
Verified starting unlockSource data confirms that no unlock is required.
Gives Isaac an Eternal Heart.
Available from the start
No unlock needed — this is available in every new save file.
What unlocking Prayer Card leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13