R Key
ItemRepentanceUnlocked
activeGame ID 636★★★★
How do you unlock R Key?
Verified starting unlockSource data confirms that no unlock is required.
Returns Isaac back to the first floor of a new run, retaining all of his stats and items.
Available from the start
No unlock needed — this is available in every new save file.
What unlocking R Key leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13