
The D6
ItemRebirthLocked
activeGame ID 105★★★★
How do you unlock The D6?
In The Binding of Isaac, The D6 is unlocked by earning the Isaac completion mark as ??? (Character).
Structured pathSource-backed requirements are mapped into trackable steps.
Re-rolls all items in the current room into other items, depending on the current room's item pool.
See the full unlock path for The D6 — 5 stepsWhat unlocking The D6 leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13