Tooth and Nail
ItemRepentanceUnlocked
passiveGame ID 663★★★★
How do you unlock Tooth and Nail?
Verified starting unlockSource data confirms that no unlock is required.
Isaac periodically turns into a spiked statue, briefly becoming invulnerable and dealing contact damage.
Available from the start
No unlock needed — this is available in every new save file.
What unlocking Tooth and Nail leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13