Toxic Shock
ItemAfterbirthUnlocked
passiveGame ID 350★★★★
How do you unlock Toxic Shock?
Verified starting unlockSource data confirms that no unlock is required.
Upon entering a room, poisons all enemies, dealing double Isaac's tear damage. Killing enemies leaves a small, short-lasting pool of green creep on the ground.
Available from the start
No unlock needed — this is available in every new save file.
What unlocking Toxic Shock leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13