
Trisagion
ItemAfterbirth+Locked
passiveGame ID 533★★★★
How do you unlock Trisagion?
In The Binding of Isaac, Trisagion is unlocked by unlocking Trisagion (Achievement).
Structured pathSource-backed requirements are mapped into trackable steps.
Tears are replaced with piercing white blasts of light that deal less damage but can damage the same enemy multiple times.
How to unlock: Take 25 Angel Rooms items
What unlocking Trisagion leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13