Vasculitis
ItemRepentanceUnlocked
passiveGame ID 657★★★★
How do you unlock Vasculitis?
Verified starting unlockSource data confirms that no unlock is required.
Enemies explode into tears upon death, which inherit the effects of Isaac's tears.
Available from the start
No unlock needed — this is available in every new save file.
What unlocking Vasculitis leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13