Progression route

The Path to Soul of Apollyon

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The path to unlock Soul of Apollyon in The Binding of Isaac has 4 steps.

4 requirements remaining0%

Path progress

Paths end with clear instructions for actions that cannot be tracked automatically.

Next steps

The Empty
Tainted Apollyon
Tainted Apollyon → Hush (normal)

Soul of Apollyon (Achievement)

All of

Tainted Apollyon → Hush

How to reach Hush: Defeat Mom's Heart for the 10th time to unlock Blue Womb. Defeat Mom's Heart or It Lives! within 30 minutes and enter the door to Blue Womb. Defeat Hush in Blue Womb.

Tainted Apollyon

The Empty

How to unlock: Use Red Key (etc.) to open the hidden closet in Home as Apollyon

Tainted Apollyon → Boss Rush

React Flow