Progression route

The Path to Anima Sola

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The path to unlock Anima Sola in The Binding of Isaac has 4 steps.

4 requirements remaining0%

Path progress

Paths end with clear instructions for actions that cannot be tracked automatically.

Next steps

The Deserter
Tainted Jacob
Tainted Jacob → Delirium (normal)

Anima Sola (Item)

Anima Sola (Achievement)

Tainted Jacob → Delirium

How to reach Delirium: Defeat Hush to unlock The Void. A Void portal can appear after a major boss; defeating Hush guarantees one. Defeat Delirium, the main boss of The Void.

Tainted Jacob

The Deserter

How to unlock: Use Red Key (etc.) to open the hidden closet in Home as Jacob and Esau

React Flow