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Dear God

Amnesia

PillRebirthUnlocked

How do you unlock Amnesia?

Verified starting unlockSource data confirms that no unlock is required.

Replaces the floor map with a ? for the rest of the floor, identical to the effect of Curse of the Lost. If no other curses are active for the floor, the Curse of the Lost will appear under the level name when the map key is held. This effect can be negated by picking up Black Candle, but will not prevent future uses of the Amnesia pill from giving the Curse of the Lost effect. Also the only pill to have its flavor text appear on a piece of paper as curses do.

Available from the start

No unlock needed — this is available in every new save file.

What unlocking Amnesia leads to

Nothing depends on this yet.

Source: bindingofisaacrebirth.wiki.gg

Imported 2026-09-13

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