Bad Trip
PillRebirthUnlocked
How do you unlock Bad Trip?
Verified starting unlockSource data confirms that no unlock is required.
Deals a full heart of damage to Isaac. Using a Bad Trip pill while Isaac only has a single heart left or less turns it into a Full Health pill. This doesn't count as damage for the purposes of Devil Room/Angel Room generation odds or score reduction.
Available from the start
No unlock needed — this is available in every new save file.
What unlocking Bad Trip leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13