Explosive Diarrhea
PillRebirthUnlocked
How do you unlock Explosive Diarrhea?
Verified starting unlockSource data confirms that no unlock is required.
Spawns a lit bomb behind Isaac every second for five seconds.
Available from the start
No unlock needed — this is available in every new save file.
What unlocking Explosive Diarrhea leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13