Health Up
PillRebirthUnlocked
How do you unlock Health Up?
Verified starting unlockSource data confirms that no unlock is required.
Adds one empty red heart container.
Available from the start
No unlock needed — this is available in every new save file.
What unlocking Health Up leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13