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Soul of Bethany

RuneRepentanceLocked

How do you unlock Soul of Bethany?

In The Binding of Isaac, Soul of Bethany is unlocked by earning every normal-mode completion mark as Tainted Bethany.

Structured pathSource-backed requirements are mapped into trackable steps.

Spawns 6 Book of Virtues wisps with random properties.

See the full unlock path for Soul of Bethany — 5 steps

Soul of Bethany (Achievement)
- All of
  - Tainted Bethany → Hush (normal)
    1. Defeat Mom's Heart for the 10th time to unlock Blue Womb. source
    2. Defeat Mom's Heart or It Lives! within 30 minutes and enter the door to Blue Womb. source
    3. Defeat Hush in Blue Womb. source
  - Tainted Bethany → Boss Rush (normal)

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What unlocking Soul of Bethany leads to

Nothing depends on this yet.

Source: bindingofisaacrebirth.wiki.gg

Imported 2026-09-13