
Soul of Eve
RuneRepentanceLocked
How do you unlock Soul of Eve?
In The Binding of Isaac, Soul of Eve is unlocked by earning every normal-mode completion mark as Tainted Eve.
Structured pathSource-backed requirements are mapped into trackable steps.
14 Dead Bird familiars fly in and attack enemies. They last 10 seconds and will begin to leave after the limit, but will stay as long as an enemy is alive. They will disappear if Isaac leaves the room.
See the full unlock path for Soul of Eve — 5 stepsWhat unlocking Soul of Eve leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13