Soul of Jacob and Esau

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How do you unlock Soul of Jacob and Esau?

In The Binding of Isaac, Soul of Jacob and Esau is unlocked by earning every normal-mode completion mark as Tainted Jacob.

Structured pathSource-backed requirements are mapped into trackable steps.

Spawns Esau as a temporary secondary character, controlled at the same time as Isaac. He dies with no consequences if his health runs out, and disappears when Isaac leaves the room. Esau has random items equal to the number of items Isaac has, each based on the pools of the items Isaac's were obtained from.

See the full unlock path for Soul of Jacob and Esau — 5 steps

Soul of Jacob and Esau (Achievement)
- All of
  - Tainted Jacob → Hush (normal)
    1. Defeat Mom's Heart for the 10th time to unlock Blue Womb. source
    2. Defeat Mom's Heart or It Lives! within 30 minutes and enter the door to Blue Womb. source
    3. Defeat Hush in Blue Womb. source
  - Tainted Jacob → Boss Rush (normal)

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What unlocking Soul of Jacob and Esau leads to

Nothing depends on this yet.

Source: bindingofisaacrebirth.wiki.gg

Imported 2026-09-13