
Soul of Magdalene
RuneRepentanceLocked
How do you unlock Soul of Magdalene?
In The Binding of Isaac, Soul of Magdalene is unlocked by earning every normal-mode completion mark as Tainted Magdalene.
Structured pathSource-backed requirements are mapped into trackable steps.
Surrounds Isaac with a bubbling red aura for the current room. All enemies killed drop Half Red Hearts that disappear in 2 seconds.
See the full unlock path for Soul of Magdalene — 5 stepsWhat unlocking Soul of Magdalene leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13