
Soul of Samson
RuneRepentanceLocked
How do you unlock Soul of Samson?
In The Binding of Isaac, Soul of Samson is unlocked by earning every normal-mode completion mark as Tainted Samson.
Structured pathSource-backed requirements are mapped into trackable steps.
Isaac turns berserk for 10 seconds, replacing his tears with a melee jawbone club and gaining +0.4 Speed, some Tears, and +3 flat Damage.
See the full unlock path for Soul of Samson — 5 stepsWhat unlocking Soul of Samson leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13