Soul of the Lost

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How do you unlock Soul of the Lost?

In The Binding of Isaac, Soul of the Lost is unlocked by earning every normal-mode completion mark as Tainted Lost.

Structured pathSource-backed requirements are mapped into trackable steps.

Turns Isaac into a ghost for the current room as if he touched the White Fire Place in Downpour II / Dross II, temporarily granting The Lost's properties.

See the full unlock path for Soul of the Lost — 5 steps

Soul of the Lost (Achievement)
- All of
  - Tainted Lost → Hush (normal)
    1. Defeat Mom's Heart for the 10th time to unlock Blue Womb. source
    2. Defeat Mom's Heart or It Lives! within 30 minutes and enter the door to Blue Womb. source
    3. Defeat Hush in Blue Womb. source
  - Tainted Lost → Boss Rush (normal)

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What unlocking Soul of the Lost leads to

Nothing depends on this yet.

Source: bindingofisaacrebirth.wiki.gg

Imported 2026-09-13