Cartridge
TrinketRebirthUnlocked
How do you unlock Cartridge?
Verified starting unlockSource data confirms that no unlock is required.
Chance to trigger The Gamekid effect upon taking damage.
Available from the start
No unlock needed — this is available in every new save file.
What unlocking Cartridge leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13