Endless Nameless
TrinketAfterbirthUnlocked
How do you unlock Endless Nameless?
Verified starting unlockSource data confirms that no unlock is required.
Has a 25% chance of creating a duplicate of any pill, card, or rune Isaac uses.
Available from the start
No unlock needed — this is available in every new save file.
What unlocking Endless Nameless leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13