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Samson's Lock

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How do you unlock Samson's Lock?

In The Binding of Isaac, Samson's Lock is unlocked by earning the The Lamb completion mark as Samson (Character).

Structured pathSource-backed requirements are mapped into trackable steps.

1/15 chance to gain +0.5 damage for the current room each time an enemy dies.

Samson's Lock (Achievement)
- Samson (Character) → The Lamb (normal)
  1. Defeat Satan 5 times to unlock The Negative. source
  2. The Negative is a guaranteed drop from Mom; take it, then defeat Satan in Sheol and touch the chest to enter Dark Room. source
  3. Find and defeat The Lamb in Dark Room. source
  - Samson (Character)

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What unlocking Samson's Lock leads to

Nothing depends on this yet.

Source: bindingofisaacrebirth.wiki.gg

Imported 2026-09-13